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The pharmacokinetics of amoxycillin and clavulanic acid are closely allied and neither are adversely affected by the presence of food in the stomach. Однако повышение активности CYP3A может иметь клиническое значение у некоторых больных, одновременно принимающих ЛС, метаболизируемые в основном CYP3A, и имеющие узкое терапевтическое окно.
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